COURSE INTRODUCTION AND APPLICATION INFORMATION

Course Name
Scientific Basis of Medicine VI
Code
Semester
Theory
(hour/week)
Application/Lab
(hour/week)
Local Credits
ECTS
SBM 302
Spring
18
2
19
18
Prerequisites
None
Course Language
English
Course Type
Required
Course Level
First Cycle
Mode of Delivery -
Teaching Methods and Techniques of the Course
Course Coordinator
Course Lecturer(s)
Assistant(s)
Course Objectives This course covers the common diseases of gastrointestinal, neurologic, psychiatric, sensorial, musculoskeletal, reproductive systems’ diseases and geriatric disorders. The aim is to learn the pathogenesis, epidemiological features, symptoms and signs of these diseases, and related diagnostic algorithms, drugs used in treatment, management and prevention strategies.
Learning Outcomes The students who succeeded in this course;
  • 1. Explain the pathogenesis of gastrointestinal system diseases, associate the related signs and symptoms with the pathophysiological mechanisms.
  • 2. Generate evidence-based diagnostic and therapeutic algorithms for selected gastrointestinal system disorders, using critical thinking and clinical reasoning principles.
  • 3. Explain the management principles and options for gastrointestinal disorders and describe the mechanisms of action and adverse effects of drugs used in the management of these disorders.
  • 4. Explain the pathogenesis of sensorineural disorders, associate the related signs and symptoms with the pathophysiological mechanisms.
  • 5. Generate evidence-based diagnostic and therapeutic algorithms for selected sensorineural disorders, using critical thinking and clinical reasoning principles.
  • 6. Explain management principles and options for sensorineural disorders and describe the mechanisms of action and adverse effects of drugs used in the management of these disorders.
  • 7. Explain the pathogenesis of musculoskeletal system diseases, associate the related signs and symptoms with the pathophysiological mechanisms.
  • 8. Generate evidence-based diagnostic and therapeutic algorithms for selected musculoskeletal system diseases, using critical thinking and clinical reasoning principles.
  • 9. Explain management principles and options for musculoskeletal disorders and describe the mechanisms of action and adverse effects of drugs used in the management of these disorders.
  • 10. Explain the pathogenesis of skin diseases, associate the related signs and symptoms with the pathophysiological mechanisms, generate evidence-based diagnostic and therapeutic algorithms for selected skin diseases, using critical thinking and clinical reasoning principles.
  • 11. Explain management principles and options for skin diseases and describe the mechanisms of action and adverse effects of drugs used in the management of these disorders.
  • 12. Explain the pathogenesis of psychiatric diseases, associate the related signs and symptoms with the pathophysiological mechanisms.
  • 13. Generate evidence-based diagnostic and therapeutic algorithms for selected psychiatric diseases, using critical thinking and clinical reasoning principles.
  • 14. Explain management principles and options for psychiatric disorders and describe the mechanisms of action and adverse effects of drugs used in the management of these disorders.
  • 15. Explain the pathogenesis of reproductive system diseases, associate the related signs and symptoms with the pathophysiological mechanisms.
  • 16. Generate evidence-based diagnostic and therapeutic algorithms for selected reproductive system diseases, using critical thinking and clinical reasoning principles.
  • 17. Explain management principles and options for reproductive system disorders and describe the mechanisms of action and adverse effects of drugs used in the management of these disorders.
  • 18. Explain the early and late pregnancy problems, list their symptoms and signs with the pathophysiological mechanisms, generate diagnostic and therapeutic algorithm using critical thinking and clinical reasoning principles.
  • 19. Define the system changes in elderly, explain the pathophysiology of geriatric syndromes and reason the principles of geriatric assessment and treatment.
  • 20. Define the relation of diseases with lifestyle behaviors and propose lifestyle interventions for prevention and treatment of lifestyle-related disorders.
Course Description In this course, the common clinical pathologies of the nervous system, sensorial, psychiatric, musculoskeletal, reproductive systems and geriatric disorders, and related evidence based diagnostic and therapeutic approaches, preventive strategies, and management of emergency situations will be evaluated.
Related Sustainable Development Goals

 



Course Category

 Core Courses
Major Area Courses
X
Supportive Courses
Media and Managment Skills Courses
Transferable Skill Courses

 

WEEKLY SUBJECTS AND RELATED PREPARATION STUDIES

Week Subjects Required Materials
1 Introduction to the course, Normal structure and function of gastrointestinal system diseases, Esophagus and stomach diseases Hammer GD, McPhee SJ. Pathophysiology of Disease: An introduction to Clinical Medicine, 8th Edition, McGraw Hill Education, 2019. Chapter 13 Gastrointestinal Disease
2 Intestinal diseases  Hammer GD, McPhee SJ. Pathophysiology of Disease: An introduction to Clinical Medicine, 8th Edition, McGraw Hill Education, 2019. Chapter 13 Gastrointestinal Disease  Gerard M. Doherty. Current Diagnosis and Treatment in Surgery 14e, by McGraw-Hill Education 2015. ISBN 978-0-07-179211-0  F. Charles Brunicardi, Dana K. Andersen, Timothy R. Billiar, David L. Dunn, Lillian S. Kao, John G. Hunter, Jeffrey B. Matthews, Raphael E. Pollock. Schwartz's Principles of Surgery, 11e, by McGraw-Hill Education, 2019. Set ISBN 978-1-259-83535-3; MHID 1-259-83535-9
3 Liver diseases  Hammer GD, McPhee SJ. Pathophysiology of Disease: An introduction to Clinical Medicine, 8th Edition, McGraw Hill Education, 2019. Chapter 14 Liver Disease  Gerard M. Doherty. Current Diagnosis and Treatment in Surgery 14e, by McGraw-Hill Education 2015. ISBN 978-0-07-179211-0  F. Charles Brunicardi, Dana K. Andersen, Timothy R. Billiar, David L. Dunn, Lillian S. Kao, John G. Hunter, Jeffrey B. Matthews, Raphael E. Pollock. Schwartz's Principles of Surgery, 11e, by McGraw-Hill Education, 2019. Set ISBN 978-1-259-83535-3; MHID 1-259-83535-9
4 Liver diseases Hammer GD, McPhee SJ. Pathophysiology of Disease: An introduction to Clinical Medicine, 8th Edition, McGraw Hill Education, 2019. Chapter 14 Liver Disease
5 Normal structure and function of sensorial and nervous system, Nervous system disorders Hammer GD, McPhee SJ. Pathophysiology of Disease: An introduction to Clinical Medicine, 8th Edition, McGraw Hill Education, 2019. Chapter 7 Nervous System Disorders
6 Sensorial and nervous system disorders  Yvonne Chan, John C. Goddard. K.J. Lee’s Essential Otolaryngology: Head and Neck Surgery, 12e by McGraw-Hill Education 2019. ISBN 978-1-260-12223-7  Hammer GD, McPhee SJ. Pathophysiology of Disease: An introduction to Clinical Medicine, 8th Edition, McGraw Hill Education, 2019. Chapter 7 Nervous System Disorders
7 Sensorial and nervous system disorders Hammer GD, McPhee SJ. Pathophysiology of Disease: An introduction to Clinical Medicine, 8th Edition, McGraw Hill Education, 2019. Chapter 7 Nervous System Disorders
8 Sensorial and nervous system disorders Hammer GD, McPhee SJ. Pathophysiology of Disease: An introduction to Clinical Medicine, 8th Edition, McGraw Hill Education, 2019. Chapter 7 Nervous System Disorders
9 Sensorial and nervous system disorders Hammer GD, McPhee SJ. Pathophysiology of Disease: An introduction to Clinical Medicine, 8th Edition, McGraw Hill Education, 2019. Chapter 7 Nervous System Disorders
10 Psychiatric disorders  Sadock BJ, Sadock VA, Ruiz P. Kaplan and Sadock's Comprehensive Textbook of Psychiatry, 10e by Lippincott Williams & Wilkins, 2017. ISBN 9781451100471  Sadock BJ, Sadock VA, Ruiz P. Kaplan and Sadock's Synopsis of Psychiatry: Behavioral Science/Clinical Psychiatry, by Lippincott Williams & Wilkins, 2015. ISBN 9781451194340
11 Normal structure and function of sensorial and musculoskeletal system Mark D. Miller & Stephen R. Thompson. Miller's Review of Orthopaedics, 8th Edition Elsevier 2019. ISBN 9780323609784
12 Musculoskeletal system disorders Hammer GD, McPhee SJ. Pathophysiology of Disease: An introduction to Clinical Medicine, 8th Edition, McGraw Hill Education, 2019. Chapter 24 Inflammatory Rheumatic Diseases
13 Skin diseases Hammer GD, McPhee SJ. Pathophysiology of Disease: An introduction to Clinical Medicine, 8th Edition, McGraw Hill Education, 2019. Chapter 8 Diseases of Skin
14 Normal structure and function of female reproductive system, Early and late pregnancy problems Hammer GD, McPhee SJ. Pathophysiology of Disease: An introduction to Clinical Medicine, 8th Edition, McGraw Hill Education, 2019. Chapter 22 Disorders of Female Reproductive Tract
15 Female genital system diseases and pathologies  Hammer GD, McPhee SJ. Pathophysiology of Disease: An introduction to Clinical Medicine, 8th Edition, McGraw Hill Education, 2019. Chapter 22 Disorders of Female Reproductive Tract  DeCherney AH, Nathan L,Laufer N, Roman AS. Current Diagnosis& Treatment: Obstetrics&Gynecology, 12e, 2013. ISBN 978-0-07-183390-5  Cunningham FG, Leveno KJ, Bloom SL, Dashe JS, Hoffman BL, Casey BM, Spong CY. Williams Obstetrics, 25e, 2014 by McGraw-Hill Education. ISBN 978-1-259-64432-0
16 Female genital system diseases and pathologies, Normal structure and function of male reproductive system  DeCherney AH, Nathan L,Laufer N, Roman AS. Current Diagnosis& Treatment: Obstetrics&Gynecology, 12e, 2013. ISBN 978-0-07-183390-5  Hoffman BL, Schorge JO, Bradshaw KD, Halvorson LM, Schaffer JI, Corton MM. Williams Gynecology, 3e, 2016 by McGraw-Hill Education. ISBN 978-0-07-184908-1  Hammer GD, McPhee SJ. Pathophysiology of Disease: An introduction to Clinical Medicine, 8th Edition, McGraw Hill Education, 2019. Chapter 23 Disorders of Male Reproductive Tract
17 Male genital system diseases and pathologies, Common problems in elderly and geriatric pharmacology McAninch JW, Lue TF. Smith&Tanagho’s General Urology, 18th Ed.2013. ISBN 978-0-07-162497-8 Chapter 44 Male Infertility, Chapter 45 The Aging Male
18 Genital system diseases and pathologies
Course Notes/Textbooks
  1. Greenberg, Aminoff, Simon. Clinical Neurology, 2012
  2. Clinically Oriented Anatomy 7th Ed. Keith L. Moore, Anne M. R. Agur, Arthur F. Dalley, 2014
  3. Neuroanatomy Through Clinical Cases, Second Edition, Text with Interactive eBook (Blumenfeld). Hal Blumenfeld, 2010
  4. Medical Physiology Ganong. Kim E. Barrett, 2012
  5. Andreoli, Carpenter, Griggs, Benjamin 7th Ed. Andreoli and Carpenter’s Cecil Essentials Of Medicine, 2016
  6. Clinical Biochemistry, An Illustrated Colour Text. Gaw, Murphy, Srivastava, 2013
  7. Raphael Rubin, David S. Strayer. Rubin's Pathology: Clinicopathologic Foundations of Medicine, 2014
  8. Williams Gynecology, 2nd Edition, Barbara L. Hoffman, John O. Schorge, Joseph I. Schaffer, Lisa M. Halvarson, Karen D. Bradshaw, F. Gary Cunningham.2012. ISBN: 978-0-07-171672-7 MHID: 0-07-171672-6
  9. Williams Obstetrics, 24th edition, edited by] F. Gary Cunningham [and seven others].2014. ISBN 978-0-07-179893-8, MHID:0-07-1798933-5
  10. Robbins and Cotran Pathologic Basis of Disease, Ninth Ed., Elsevier Saunders, 2015, ISBN: 9780323266161
  11. Basic and clinical pharmacology, Edited by Bertram G. Katzung; associate editors, Susan B. Masters, Anthony J. Trevor. ISBN-ISSN:978-0-07-176401-8, New York: McGraw-Hill Medical, 2015
  12. Schwartz Principles of Surgery 10th edition 2015, McGraw Hill Education, New York Chicago, ISBN: 978-0-07-180092-1.
  13. Nelson Essentials of Pediatrics, Karen J. Marcdante, Robert M. Kliegman, International edition, 2015 ISBN:978-0-323-22700-1
  14. Smith and Tanagho's General Urology 18th Edition by Jack W. McAninch (Author), Tom F. Lue (Author) ISBN-13: 978-0071624978 ISBN-10: 007162497X 
Suggested Readings/Materials
  1. Gray's Anatomy for Students: With STUDENT CONSULT Online Access, 3e 3rd Edition. Richard L. Drake, A. Wayne Vogl, Adam W. M. Mitchell, 2015
  2. Histology: A Text and Atlas, with Correlated Cell and Molecular Biology, 6th Edition. Michael H. Ross, Wojciech Pawlina, 2016
  3. Harper’s Illustrated Biochemistry, 30th Ed, Lange. Rodwell VW, Bender DA, Botham RM, Kennelly PJ, Weil PA. 2015
  4. Physiology Cases and Problems (Board Review Series) Fourth Edition. Linda Costanzo, 2012
  5. The Developing Human: Clinically Oriented Embryology, 10th Edition. Keith L. Moore, T. V. N. Persaud, Mark G. Torchia, 2016
  6. Molecular Biology of the Cell. Alberts, Johnson, Lewis, Raff., 2015Essential Obstetrics and Gynaecology, Ian M. Symonds, Sabaratnam Arulkumaran ; editor emeritus, E. Malcolm Symonds, 5th edition, 2013. ISBN: 9780702030765
  7. Obstetrics and Gynecology at a Glance, Norwitz, Errol R. 4th edition, 2013. ISBN: 978-1-118-73234-2
  8. Cakmak H and Taylor HS. Implantation failure: molecular mechanisms and clinical treatment. Human Reproduction Update, 17(2); 2011: 242–253.            

 

EVALUATION SYSTEM

Semester Activities Number Weigthing
Participation
Laboratory / Application
Field Work
Quizzes / Studio Critiques
4
10
Portfolio
Homework / Assignments
2
10
Presentation / Jury
Project
Seminar / Workshop
Oral Exam
1
10
Midterm
4
40
Final Exam
1
30
Total

Weighting of Semester Activities on the Final Grade
70
Weighting of End-of-Semester Activities on the Final Grade
30
Total

ECTS / WORKLOAD TABLE

Semester Activities Number Duration (Hours) Workload
Course Hours
(Including exam week: 18 x total hours)
18
18
324
Laboratory / Application Hours
(Including exam week: 18 x total hours)
18
2
Study Hours Out of Class
18
3
54
Field Work
Quizzes / Studio Critiques
4
4
Portfolio
Homework / Assignments
2
10
Presentation / Jury
Project
Seminar / Workshop
Oral Exam
1
8
Midterms
4
10
Final Exams
1
30
    Total
528

 

COURSE LEARNING OUTCOMES AND PROGRAM QUALIFICATIONS RELATIONSHIP

#
 Program Competencies/Outcomes
* Contribution Level
1
2
3
4
5
1

Explain the normal structure and functions of the human body at the molecular, cellular, tissue, organ and system levels, associate them with suggestions, practices and clinical situations (nutrition, exercise, vaccination, mental health, etc.); to protect and improve the health of individuals.

 X
2

Describe the mechanisms of diseases at the molecular, cellular, tissue, organ and system levels and make evidence-based decisions by associating them with disease findings, diagnosis and treatment approaches.

 X
3

Consider the ethical principles, scientific facts, legal regulations and the biopsychosocial and cultural characteristics of the patient in the medical decision making process. Place importance and respect the autonomy of patients and the confidentiality of patient information, within the framework of the law and the provisions of healthcare application standards.

 X
4

Prioritize patient safety to minimize malpractice by carrying out risk assessment, take the necessary precautions, perform the necessary medical practice and record them.

 X
5

Communicate healthily, openly and effectively with healthcare workers, patients and their relatives, with the communication structured on empathy and care, trust and constructiveness; while being respectful to language, belief, race and cultural characteristics.

 X
6

By bearing in mind the patients’ values, beliefs, priorities, and needs; provide evidence-based options and include them in the decision making process.

 X
7

Preserve our planet’s resources and consider its effects on the public and individual’s health, advocate to disseminate healthy lifestyle behaviors and modify factors that affect health adversely.

 X
8

Reach current, valid and reliable information effectively using technology. Critically evaluate this information for solving problems in an evidence-based medical decision-making process, bearing in mind prevention, diagnosis, and management of diseases.

 X
9

Identify problems, create hypotheses, conduct research and employ teamwork to analyze results for generation and dissemination of health-related scientific knowledge.
10

By taking feedback and evaluating their performance, determine the areas and options for improvement and implement them within a plan.
11

Care for their own personal health, safety and appearance, take the necessary precautions in order to set an example for their colleagues and society.
12

Continuously renew themselves in their medical knowledge by always bearing in mind their commitment to lifelong learning principles.

 X
13

Using various communication tools, share their professionally gained knowledge in the field of healthcare, opinions, experiences, and evaluations with institutions, colleagues and the public.  Advocate for healthcare and contribute to developing policies to protect and improve it.

 X

*1 Lowest, 2 Low, 3 Average, 4 High, 5 Highest